Case Western Reserve University

Structural Biology and Biophysics Training Program (SBB-TP)

You're interested in applying quantitative skills to biomedical research.

So, what will you discover?

Meet (upper row left to right) Mark, Quentin, James, and (lower row left to right) Ross and Seong-Ki. They made the successful transition in our Ph.D. program to research in structural biology or biophysics after having majored in physics or biomedical engineering.

Interested in applying your quantitative problem solving skills to biomedical research?

The Structural Biology and Biophysics Training Program provides an entry point to graduate education in the areas of Structural Biology, Molecular Biophysics, and Cellular Biophysics. Research programs in these areas are present in the Departments of Biochemistry, Pharmacology, and Physiology & Biophysics.

Structural Biology is concerned with the molecular structure of biological macromolecules or macromolecular complexes that carry out most of the vital functions of cells. Structure determination is achieved with methods such as X-ray and neutron crystallography, nuclear magnetic resonance (NMR), ultra fast laser spectroscopy, (cryo-) electron microscopy (EM/cryo-EM), as well as computational modeling.

Molecular biophysics seeks to understand biomolecular systems and explain biological function in terms of molecular structure, structural organization, and dynamic behavior at various levels of complexity, using methods such as amide-hydrogen exchange, or chemical footprinting in conjunction with mass spectrometry and computational modeling.

Cellular Biophysics uses quantitative physical/physical-chemical concepts and methods as well as mathematical modeling to study the dynamics of membrane and cellular functions, for example, with patch-clamp electrophysiology or live cell light imaging.

Follow this link to learn more about the SBB Training Program

 

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